![]() Blood samples were obtained, and serum concentrations of vitamin D, calcium, and magnesium were determined. Migraine severity questionnaire (MIGSEV) and the Migraine Disability Assessment (MIDAS) questionnaire were given and illustrated to the participants. After obtaining basic data, a visual analogue scale (VAS) for the severity of migraine pain was assessed. Thirty healthy individuals and 60 age- and sex-matched migraineurs (22 chronic and 38 episodic migraineurs), diagnosed according to the International Headache Society criteria (ICHD-III), were recruited. We investigated the possible relationship between vitamin D level and its related minerals (calcium and magnesium) and migraine characteristics in patients. The effect of vitamin D on various neurological disorders is thought to be exerted either directly via its specific receptors or through the related minerals. Migraine, although, is a prevalent disease its pathogenesis is complex and still not fully elucidated.
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